upstream timed out (110: Connection timed out) while reading upstream

2018/04/26 23:34:39 [error] 10872#0: *268906 upstream timed out (110: Connection timed out) while reading upstream, client: 119.103.223.107, server: ****, request: “GET /**** HTTP/1.1”, upstream: “****”, host: “****”

#fastcgi_connect_timeout 600;
#fastcgi_read_timeout 600;
#fastcgi_send_timeout 600;
proxy_connect_timeout 600;
proxy_read_timeout 600;
proxy_send_timeout 600;

upstream timed out (110: Connection timed out) while reading upstream,

upstream timed out (110: Connection timed out) while reading response header from upstream